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Saturday, April 23, 2011

About Alzheimer's Disease: Family History of Alzheimer's Disease

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From Andrew Rosenzweig, MD, your Guide to Alzheimer's Disease
It's pretty well accepted that for the common, late-onset type of Alzheimer's disease that accounts for 95% of all cases, family history plays an important role in one's risk. With a recent study showing that whether your mother had Alzheimer's is more important to your risk than whether your father had it, I thought I'd devote today's newsletter to this topic of family history.

Importance of Family History as Risk Factor for Alzheimer's
People who have had a parent or sibling that developed Alzheimer's disease are two to three times more likely to develop the disease than those with no family history of Alzheimer's. If more than one close relative has been affected, the risk increases even more.... Read more

Family History and the APOE Gene
Despite many new findings about the genetics of Alzheimer's disease,when it comes to one's risk of getting Alzheimer's nothing comes close to the importance of ApoE. ApoE 4 is one of several variants of the ApoE gene. Those who have the ApoE 4 gene are three to eight times more likely to develop Alzheimer's disease than those who do not carry ApoE 4.... Read more

Family History Isn't Everything
Some people with a family history of Alzheimer's won't develop the disease, while others with no family history will develop Alzheimer's. This suggests that Alzheimer's is not totally controlled by genetics; therefore, lifestyle and other factors most likely play an important role in our risk for developing the disease.... Read more

Family History Less Important for Lewy Body Dementia
Although Alzheimer's Disease and Lewy Body Dementia share many similarities, family history doesn't seem to be one of them. Some cases of Lewy Body Dementia have been reported within families, but for the most part, the disease occurs with no family history....

 


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This newsletter is written by:
Andrew Rosenzweig, MD
Alzheimer's Disease Guide
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